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Monday, August 25, 2025

Zogenix


Zogenix – Product Catalog

  • Fintepla → Generic: fenfluramine hydrochloride oral solution → Indication:

    • Dravet syndrome (rare epilepsy)

    • Lennox–Gastaut syndrome (LGS)
      → Dose: Oral solution 2.2 mg/mL; titrated to max 26 mg/day (weight-based dosing)

  • Zohydro ER → Generic: hydrocodone bitartrate extended-release → Indication: Severe chronic pain requiring long-term opioid treatment → Dose: Capsules 10–50 mg ER (q12h)
    (Note: faced significant controversy for opioid safety; withdrawn/limited use in some regions.)

  • Relday (pipeline, never commercialized) → Generic: risperidone once-monthly SQ injection (long-acting) → Indication: Schizophrenia → Status: Phase III, discontinued

  • MT1621 (pipeline, later with UCB) → Generic: deoxynucleoside therapy (thymidine/uridine) → Indication: TK2 deficiency (rare mitochondrial DNA depletion syndrome) → Developmental therapy, orphan drug status


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