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Monday, August 25, 2025

Sigma-Tau Pharmaceuticals


Sigma-Tau Pharmaceuticals – Product Catalog (A–Z)

  • Adagen → Generic: pegademase bovine (PEG-ADA enzyme replacement) → Indication: Severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency → Dose: IM injection 250–500 IU/m² weekly

  • Cystadane → Generic: betaine anhydrous → Indication: Homocystinuria (to reduce homocysteine levels) → Dose: Oral powder, 1 g per scoop; typical 3–6 g bid

  • Depocyt → Generic: cytarabine liposome injection → Indication: Lymphomatous meningitis (oncology) → Dose: Intrathecal injection 50 mg every 2 weeks

  • Oncaspar (later under Shire/Takeda) → Generic: pegaspargase → Indication: Acute lymphoblastic leukemia (ALL) → Dose: IV/IM injection 750 IU/m² every 2 weeks

  • Procysbi (co-developed, later under Horizon) → Generic: cysteamine bitartrate (delayed-release) → Indication: Nephropathic cystinosis → Dose: DR capsules 25 mg, 75 mg

  • SupraVit / Specialty Vitamins (regional) → Generic: multivitamin formulations → Indication: Nutritional supplementation → Dose: Tablets/capsules, regional OTC

  • Zanolimumab (developmental) → Generic: anti-CD4 monoclonal antibody → Indication: T-cell lymphoma (investigational, discontinued) → Dose: IV infusion (trial only)



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