Introduction
Haemorrhoids, commonly referred to as piles, are vascular cushions in the anal canal that become symptomatic when swollen, inflamed, or prolapsed. They are a normal anatomical structure that contributes to continence by providing a seal for the anal canal. When these cushions enlarge pathologically, they cause bleeding, discomfort, and sometimes prolapse or thrombosis.
Anatomy and Classification
Normal anatomy
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Haemorrhoidal cushions are composed of blood vessels, connective tissue, and smooth muscle.
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Located in the submucosa of the anal canal at three primary positions: left lateral, right anterior, and right posterior.
Classification
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By location:
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Internal haemorrhoids: Arise above the dentate line, covered by columnar epithelium, innervated by visceral nerves (painless).
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External haemorrhoids: Arise below the dentate line, covered by squamous epithelium, innervated by somatic nerves (painful if thrombosed).
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Mixed haemorrhoids: Features of both.
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By grade (internal haemorrhoids):
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Grade I: Bulge into the lumen but do not prolapse.
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Grade II: Prolapse during defecation but reduce spontaneously.
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Grade III: Prolapse during defecation and require manual reduction.
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Grade IV: Irreducible prolapse, may become strangulated.
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Etiology and Risk Factors
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Chronic constipation or diarrhoea.
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Straining during defecation.
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Low-fibre diet.
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Prolonged sitting on the toilet.
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Pregnancy (increased pelvic pressure).
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Obesity.
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Aging (weakening of supporting connective tissue).
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Heavy lifting or increased intra-abdominal pressure.
Pathophysiology
Increased pressure within the haemorrhoidal plexus leads to engorgement, stretching, and weakening of supporting tissue. This results in symptomatic haemorrhoids, which may bleed, prolapse, or thrombose.
Clinical Features
Symptoms:
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Bright red rectal bleeding (on toilet paper, in the pan, or coating stool).
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Anal itching or irritation.
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Prolapse of tissue during defecation.
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Pain (especially with thrombosed external haemorrhoids).
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Mucus discharge and soiling (in prolapsed haemorrhoids).
Signs:
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Visual inspection: External haemorrhoids, prolapsed internal haemorrhoids.
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Digital rectal examination: May detect internal haemorrhoids (not prolapsed).
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Anoscopy: Direct visualization for diagnosis and grading.
Differential Diagnosis
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Anal fissure
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Rectal prolapse
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Colorectal cancer
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Inflammatory bowel disease
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Polyps
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Perianal abscess
Investigations
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Anoscopy: Gold standard for diagnosis of internal haemorrhoids.
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Proctoscopy/sigmoidoscopy/colonoscopy: Indicated if age >40, bleeding unexplained, or malignancy suspected.
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FBC: Assess for anaemia in chronic bleeding.
Management
1. Conservative Measures (First-Line for All Grades)
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Dietary modification: Increase fibre (20–30 g/day) via diet or supplements (psyllium, methylcellulose).
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Adequate fluid intake.
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Avoid straining; respond promptly to the urge to defecate.
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Limit prolonged sitting on the toilet.
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Sitz baths (warm water immersion) for 10–15 minutes, 2–3 times daily, to relieve discomfort.
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Good anal hygiene.
2. Medical Therapy
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Topical preparations:
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Local anaesthetics (e.g., lidocaine 5% ointment) for pain relief.
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Mild corticosteroids (e.g., hydrocortisone 1% cream) short-term to reduce inflammation and itching.
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Combination products (e.g., hydrocortisone + local anaesthetic).
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Oral venoactive agents (e.g., micronized purified flavonoid fraction [diosmin/hesperidin] 500 mg twice daily) may reduce symptoms in acute flares.
3. Office-Based Procedures (for persistent symptoms or Grade II–III)
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Rubber band ligation:
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Most common for Grades I–III internal haemorrhoids.
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Rubber band applied to haemorrhoid base → ischemia → sloughing.
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Infrared coagulation: Infrared light causes coagulation and fibrosis.
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Sclerotherapy: Injection of sclerosant (e.g., 5% phenol in oil) to cause fibrosis.
4. Surgical Management (for Grade III–IV, recurrent, or complicated haemorrhoids)
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Excisional haemorrhoidectomy: Open or closed technique; definitive but more painful recovery.
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Stapled haemorrhoidopexy: Circular stapler excises mucosa above haemorrhoids and repositions them; less pain but higher recurrence risk.
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Doppler-guided haemorrhoidal artery ligation: Ultrasound probe identifies and ligates feeding arteries; less tissue excision.
Complications
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Anaemia from chronic bleeding.
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Thrombosis (especially external haemorrhoids).
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Strangulation of prolapsed haemorrhoid → gangrene.
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Recurrence after treatment.
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Post-procedure: Pain, bleeding, infection, urinary retention.
Prognosis
Most mild haemorrhoids improve with conservative measures. Advanced cases respond well to procedural or surgical treatment, but recurrence is possible, especially if lifestyle factors are not addressed.
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