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Monday, August 18, 2025

Limping in children


Limping in children is a common clinical presentation and can range from benign, self-limiting causes to serious underlying conditions requiring urgent intervention. It is defined as any deviation from a normal walking pattern, often resulting from pain, weakness, structural abnormalities, or neurological dysfunction. A thorough evaluation is essential to identify the underlying etiology and provide appropriate management.


Causes of Limping in Children

1. Trauma and Injury

  • Acute trauma such as fractures, sprains, ligament injuries, or contusions.

  • Minor injuries like stubbed toes or falls.

  • Non-accidental injury (child abuse) must be considered if the history is inconsistent with the injury.

2. Infection

  • Septic arthritis – urgent cause; hip involvement can present with sudden severe limp, fever, inability to bear weight.

  • Osteomyelitis – bone infection leading to pain, fever, and localized tenderness.

  • Viral myositis – often post-infectious, causing calf muscle pain and difficulty walking.

3. Inflammatory and Autoimmune

  • Transient synovitis – the most common cause in young children; usually follows a viral infection; hip joint inflammation causes painful limp.

  • Juvenile idiopathic arthritis (JIA) – chronic joint inflammation with stiffness, morning limp, and swelling.

4. Orthopedic/Developmental Conditions

  • Developmental dysplasia of the hip (DDH) – presents in toddlers with painless limp or leg length discrepancy.

  • Legg-Calvé-Perthes disease – avascular necrosis of the femoral head, typically in boys aged 4–8 years.

  • Slipped capital femoral epiphysis (SCFE) – affects adolescents, especially obese boys; causes hip/knee pain and limp.

  • Clubfoot, flatfoot, or limb length discrepancy – mechanical causes of abnormal gait.

5. Neoplastic

  • Leukemia – bone pain may cause intermittent limping.

  • Bone tumors (e.g., osteosarcoma, Ewing sarcoma).

6. Neurological

  • Cerebral palsy – spasticity and muscle imbalance affect gait.

  • Peripheral neuropathy or muscle disorders (e.g., muscular dystrophy).


Evaluation

History

  • Onset: sudden vs gradual.

  • Duration: acute, subacute, or chronic.

  • Associated symptoms: fever, night pain, weight loss, joint swelling, morning stiffness.

  • Trauma history.

  • Developmental milestones.

  • Family history of musculoskeletal or neurological disorders.

Physical Examination

  • Gait assessment: antalgic gait, Trendelenburg gait, toe-walking.

  • Joint examination: swelling, warmth, tenderness, range of motion.

  • Limb length measurement.

  • Neurological exam: reflexes, tone, strength.

Investigations (if needed)

  • Blood tests: CBC, ESR, CRP (infections, leukemia, inflammation).

  • Imaging:

    • X-ray of affected joint/limb.

    • Ultrasound of hip (for effusion).

    • MRI (for bone tumors, Perthes disease, osteomyelitis).

  • Joint aspiration – if septic arthritis suspected (urgent).


Management

1. Supportive and Conservative

  • Minor injuries or transient synovitis – rest, analgesics (paracetamol, ibuprofen), gradual return to activity.

  • Viral myositis – resolves with hydration and rest.

2. Infection

  • Septic arthritis/osteomyelitis – urgent hospitalization, IV antibiotics (e.g., ceftriaxone, flucloxacillin), surgical drainage if required.

3. Inflammatory

  • Juvenile idiopathic arthritis – managed with NSAIDs (ibuprofen, naproxen), disease-modifying antirheumatic drugs (methotrexate), corticosteroids if needed.

4. Orthopedic Conditions

  • DDH – bracing (Pavlik harness) in infants; surgery in older children.

  • Legg-Calvé-Perthes disease – activity restriction, physiotherapy, surgical intervention if severe.

  • SCFE – surgical pinning of femoral head to prevent progression.

5. Neoplastic

  • Leukemia or tumors – referral to oncology for chemotherapy, surgery, or radiotherapy as indicated.

6. Neurological

  • Cerebral palsy – physiotherapy, orthotics, muscle relaxants (baclofen), possible surgery.

  • Muscular dystrophy – supportive care, steroids (prednisone, deflazacort), physiotherapy.


Red Flags (Require Urgent Referral)

  • Inability to bear weight.

  • High fever with limp (possible septic arthritis).

  • Night pain waking child from sleep.

  • Progressive worsening limp.

  • Systemic symptoms (weight loss, night sweats, lethargy).

  • Asymmetry or deformity in lower limbs.


Medications (Generic Names and Usual Pediatric Doses)

  • Paracetamol (Acetaminophen): 10–15 mg/kg every 4–6 hours (max 60 mg/kg/day).

  • Ibuprofen: 5–10 mg/kg every 6–8 hours (max 40 mg/kg/day).

  • Antibiotics (for infections):

    • Ceftriaxone: 50–75 mg/kg IV daily.

    • Flucloxacillin: 25–50 mg/kg IV every 6 hours.

  • Methotrexate (for JIA): 10–15 mg/m² once weekly.

  • Corticosteroids (for inflammation): Prednisolone 1–2 mg/kg/day (short course).




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