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Tuesday, August 19, 2025

High temperature (fever) in children


A high temperature, commonly referred to as fever, is one of the most frequent symptoms in children. It is typically defined as a body temperature of 38°C (100.4°F) or higher. Fever is not a disease in itself but a clinical sign that indicates the body’s immune system is responding to an infection or other underlying cause.


Causes of Fever in Children

Fever in children can arise from a wide range of conditions:

  • Infections (most common cause):

    • Viral infections: influenza, common cold, roseola, COVID-19, chickenpox, hand-foot-and-mouth disease.

    • Bacterial infections: ear infections (otitis media), strep throat, pneumonia, urinary tract infections, meningitis, sepsis.

  • Non-infectious causes:

    • Recent immunization (post-vaccination reaction).

    • Autoimmune or inflammatory conditions (e.g., juvenile idiopathic arthritis, Kawasaki disease).

    • Malignancies (rare, but possible in persistent unexplained fever).

    • Heat exhaustion or dehydration.


Clinical Features

Children with fever may present with:

  • Warm or hot skin, flushed appearance.

  • Sweating or shivering (rigors).

  • Irritability, fussiness, or lethargy.

  • Poor feeding in infants, decreased appetite in older children.

  • Increased heart rate and breathing.

  • Associated symptoms: sore throat, cough, ear pain, vomiting, diarrhea, rash, or drowsiness depending on the cause.


Diagnosis

  • History: Onset, duration, associated symptoms, recent contacts, travel, and vaccination history.

  • Examination: Measurement of temperature (oral, tympanic, rectal, or axillary), hydration status, rash, signs of respiratory distress, meningism, or localized infection.

  • Investigations (if clinically indicated):

    • Blood tests: CBC, CRP, cultures.

    • Urinalysis and urine culture (especially in infants and toddlers).

    • Chest X-ray if pneumonia suspected.

    • Lumbar puncture in suspected meningitis.


Management and Treatment

Most fevers are self-limiting, particularly when caused by viral infections. Management depends on the underlying cause and the child’s overall condition.

1. General Care:

  • Ensure hydration: encourage fluids (oral rehydration solutions in small children).

  • Lightweight clothing, comfortable room temperature.

  • Rest and monitoring.

2. Medications (antipyretics for comfort, not for routine lowering of fever):

  • Paracetamol (Acetaminophen):

    • Dose: 10–15 mg/kg every 4–6 hours (maximum 4 doses in 24 hours).

  • Ibuprofen (in children over 3–6 months, if not contraindicated):

    • Dose: 5–10 mg/kg every 6–8 hours (maximum 4 doses in 24 hours).

  • Avoid aspirin in children due to the risk of Reye’s syndrome.

3. Antibiotics or antivirals:

  • Only if bacterial infection or specific viral illness is confirmed or highly suspected.

  • Common examples:

    • Amoxicillin for bacterial ear or throat infections (doses vary by age and weight).

    • Ceftriaxone IV for severe infections (e.g., sepsis, meningitis).

    • Oseltamivir for influenza in high-risk cases.


Red Flag Symptoms (Seek urgent medical attention if present):

  • Fever in infants under 3 months (≥38°C).

  • Fever persisting >5 days.

  • Severe lethargy, difficulty waking, persistent irritability.

  • Breathing difficulties, fast or labored breathing.

  • Convulsions (febrile seizures).

  • Rash that doesn’t blanch under pressure (petechiae or purpura).

  • Stiff neck, severe headache, photophobia.

  • Signs of dehydration: dry mouth, no tears, sunken eyes, reduced urine output.


Precautions for Parents

  • Do not overdress or heavily blanket the child.

  • Do not use cold baths; tepid sponging is rarely recommended.

  • Monitor temperature regularly.

  • Avoid unnecessary antibiotics for viral infections.

  • Ensure all vaccinations are up to date.


Drug Interactions and Considerations

  • Paracetamol: relatively safe, but overdose can cause liver toxicity. Caution in children with liver disease.

  • Ibuprofen: avoid in children with dehydration, kidney disease, or history of gastric ulcer.

  • Combining paracetamol and ibuprofen may be used in alternating doses under medical supervision, but routine combined use is discouraged.




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