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Sunday, August 31, 2025

Bluebird Bio


Bluebird Bio products


Lyfgenia®

  • Generic: lovotibeglogene autotemcel (lovo-cel)

  • Indication: gene therapy for sickle cell disease (patients ≥12 years with recurrent vaso-occlusive events)

  • Usage: one-time autologous infusion of genetically modified hematopoietic stem cells following conditioning regimen; long-term follow-up required

Skysona®

  • Generic: elivaldogene autotemcel (eli-cel)

  • Indication: treatment of cerebral adrenoleukodystrophy (CALD) in pediatric patients

  • Usage: single autologous stem cell infusion via IV after conditioning; includes long-term safety monitoring for potential risks

Zynteglo®

  • Generic: betibeglogene autotemcel (beti-cel)

  • Indication: transfusion-dependent β-thalassemia in patients aged ≥12 years without β0/β0 genotype

  • Usage: one-time autologous IV infusion of modified stem cells following conditioning regimen; intended to produce lifelong transfusion independence




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